Scientist & Research:
Dr. Lin, Botany Research Institute of Sinica
Where is the Ca2+ coming from?
Calmodulin (CaM) is an important modulator of second messenger Ca2+. But when CaM plays its role inside cells causing the falling and rising of internal Ca2+, there is always a critical issue if these Ca2+ ions are released from cellular Ca2+ stores or they are transported from external media.
Because of its non-invasive nature, NMT was able to detect the influxes of Ca2+ and directly confirm the confocal data showing an increase of internal Ca2+ concentrations.