110 North Hillside Rd., Suite 11, South Deerfield, MA 01373, USA
contact@youngerusa.com|+1-413-992-2003
Since 2001 · Massachusetts, USA

We Believe in Real Live Sciences.

YoungerUSA, LLC is the world leader in Non-invasive Micro-test Technology (NMT) — measuring the real-time exchange of ions and molecules between living systems and their environment. As a technology partner of the NMT alliances, YoungerUSA also supports the open imOmics and Global imOme Project (GiP) initiatives with instruments, software and services.

Life = f (Environment, t)

The state of a living system is a function of its environment and time. NMT reads this function — in vivo, in situ, and in real time.

Extended Biology Dogma: 
DNA → RNA → Protein → imOme → Phenotype
Inside a YoungerUSA Laboratory

The NMT Platform at Work

YoungerUSA NMT laboratory: AI high-throughput NMT workstation with microscope, Faraday cage and anti-vibration table
IAA Physiolyzer®
Commercialized System for both Endogenous and Exogenous Auxin (IAA) Fluxes Measurements
Science → recommended
2001
Founded in Massachusetts — 25 years of NMT innovation
1,000+
Peer-reviewed publications enabled by NMT, incl. Cell, Nature, Science
400+
Laboratories worldwide running NMT platforms
10-15
mol·cm-2·s-1 — femto-level flux sensitivity
Our Role in the Ecosystem

One Ecosystem — Clear Roles

NMT is YoungerUSA's own technology. imOmics and the Global imOme Project (GiP) are open scientific initiatives governed by the NMT alliances — our role is to build the instruments, software and services that make their measurements possible.

Our Technology

NMT — Non-invasive Micro-test Technology

Fully computerized, non-contact measurement of ionic and molecular fluxes from living samples — in 1D/2D/3D, with sensitivity down to the femto level. From a single pollen grain to whole zebrafish, no labeling, no grinding, no damage.

How NMT works →
Open Framework · The Alliances

imOmics — Ionic & Molecular Omics

Proposed by our founder Yue 'Jeff' Xu in 2014, imOmics studies the dynamic fluxes of ions and molecules at the interface between life and environment — the quantitative language of the function f in Life = f(Environment, t). Today it is an open framework of the NMT alliances.

NMT International Alliance ↗
Open Initiative · The Alliances

GiP — Global imOme Project

An open global initiative of the NMT International Alliance: a worldwide network of standardized, intelligent monitoring nodes building a cross-species, cross-scale, cross-region dynamic database of life–environment interactions. YoungerUSA supports it as a technology partner.

Initiative home: nmtia.org ↗
Attribution: imOmics and the Global imOme Project (GiP) are open scientific initiatives of the NMT International Alliance and the Zhongguancun NMT Industrial Alliance. YoungerUSA, LLC participates as a technology and commercialization partner.
Life = f (Environment, t)
DNA→ RNA→ Protein→ imOme→ Phenotype

From traditional wisdom to a New Biology Dogma

Rooted in the ancient Chinese wisdom of "Harmony between Heaven and Humanity" and formulated by Yue 'Jeff' Xu, the framework of Life = f(Environment, t) extends the Central Dogma with the imOme — the real-time ionic and molecular exchanges that connect genetic instructions to macroscopic phenotypes — published in NMT Communications (2025). NMT makes the imOme measurable; the alliances' open imOmics and GiP initiatives make it a shared, global science.

Read the paper ↗
Flagship Instruments

NMT Systems for Every Scale of Life

ISO 9001 certified, branded YoungerUSA, manufactured in the USA — from AI-driven high-throughput platforms to teaching editions for the next generation of scientists.

View the flagship systems

Where NMT Works

Applications Across the Life Sciences

Wherever ions and molecules cross a living membrane, NMT reads the conversation. Plant physiology is today's most popular field — and creative scientists add new fields every day.

Illustrative fluorescence microscopy: living cell spheroid approached by a microelectrode

Physiology & Medicine

Personalized chemotherapy screening, tumor-margin H⁺ imaging, neuroscience, diabetes, apoptosis and drug-efficacy evaluation.

Learn more →
Illustrative fluorescence microscopy: living green leaf with microelectrode

Plant & Crop Sciences

Stress tolerance (salt, drought, temperature), nutrient uptake, hormone dynamics (IAA), photosynthesis and plant–microbe interactions.

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Illustrative fluorescence microscopy: leaf surface with a small organism and microelectrode

Environmental Science

Biomonitoring of pollution, heavy-metal remediation, drinking-water and food-safety rapid testing, algal-bloom surveillance.

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Illustrative fluorescence microscopy: microbial colony with microelectrode

Microbiology & Marine Biology

Microbial metabolism, coral-bleaching early warning, marine ecotoxicology and space biology — plus animal science and TCM research.

Learn more →

The NMT Publication Library

1,115 peer-reviewed papers — from Cell, Nature and Science to the newest 2026 studies — organized year by year, exactly like the classic YoungerUSA archive, with instant full-archive search. News & milestones live in the Archive (link in the footer).

Browse publications by year

Become a Distributor of NMT

YoungerUSA is the world's leading manufacturer of NMT systems, with 25 years of market experience and 400+ laboratories served. As NMT, imOmics and GiP expand internationally, we welcome qualified partners worldwide. All pricing, quotation and distributor applications are handled by email.

contact@youngerusa.com