Scientist & Research:

Dr. Lin, Botany Research Institute of Sinica
Where is the Ca²⁺ coming from?

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Challenges:

Calmodulin (CaM) is an important modulator of second messenger Ca²⁺. But when CaM plays its role inside cells causing the falling and rising of internal Ca²⁺, there is always a critical issue if these Ca²⁺ ions are released from cellular Ca²⁺ stores or they are transported from external media.

NMT Solutions:

Because of its non-invasive nature, NMT was able to detect the influxes of Ca²⁺ and directly confirm the confocal data showing an increase of internal Ca²⁺ concentrations.